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ACTH loading test (suspicions of AGS)

Name ACTH loading test (suspicions of AGS)
Additional testing 17-OH progesterone
Procedure remarks Between 7:00 and 9:00 in the morning, take blood to determine the baseline value (fasting patient) and then give an IV or IM injection of e.g. 0.25 mg of Synacthen® (ACTH); afterwards, take blood samples after 30 min and 60 min; send the 3 labelled samples to the laboratory.
Clinical utility Adrenogenital syndrome (AGS), enzyme defect: 21-hydroxylase deficiency