| Name | beta-2 microglobulin in the urine |
| Specimen requirements | 1 ml of 24-hour urine 1 ml of second morning urine |
| Collection instructions | The beta-2 microglobulin is denatured in an acidic environment, including in the bladder. Immediately after being collected, the urine must be brought to a pH value of 6-8 by adding a few drops of 2n NaOH. |
| Clinical utility | marker for tubular nephropathy, assessing kidney function after transplants, nephrotic syndrome, NHL, HL, myeloma |
| Methodology | CLIA (chemiluminescence immunoassay) |
| Reference ranges | 98-320 µg/l |