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beta-2 microglobulin in the urine

Name beta-2 microglobulin in the urine
Specimen requirements 1 ml of 24-hour urine
1 ml of second morning urine
Collection instructions The beta-2 microglobulin is denatured in an acidic environment, including in the bladder. Immediately after being collected, the urine must be brought to a pH value of 6-8 by adding a few drops of 2n NaOH.
Clinical utility marker for tubular nephropathy,
assessing kidney function after transplants,
nephrotic syndrome,
NHL, HL, myeloma
Methodology CLIA (chemiluminescence immunoassay)
Reference ranges 98-320 µg/l